BindingDB logo
myBDB logout

null

SMILES: CS(=O)(=O)c1ccccc1-c1ccc(N2CCCC(NS(=O)(=O)c3ccc(s3)-c3ccon3)C2=O)c(F)c1

InChI Key: InChIKey=SGFSFNNCXKZEQZ-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50374899   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))		BDBM50374899
PNG
(CHEMBL272115)
Show SMILES CS(=O)(=O)c1ccccc1-c1ccc(N2CCCC(NS(=O)(=O)c3ccc(s3)-c3ccon3)C2=O)c(F)c1 |w:18.19|
Show InChI InChI=1S/C25H22FN3O6S3/c1-37(31,32)23-7-3-2-5-17(23)16-8-9-21(18(26)15-16)29-13-4-6-20(25(29)30)28-38(33,34)24-11-10-22(36-24)19-12-14-35-27-19/h2-3,5,7-12,14-15,20,28H,4,6,13H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
 26n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a

Bioorg Med Chem Lett 18: 2428-33 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.054
BindingDB Entry DOI: 10.7270/Q2RX9CZ8
More data for this
Ligand-Target Pair