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SMILES: CS(=O)(=O)c1ccccc1-c1ccc(N2CCCC(NS(=O)(=O)c3ccc(Cl)s3)C2=O)c(F)c1

InChI Key: InChIKey=MZFWRIWUKKIZFN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50374900   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))		BDBM50374900
PNG
(CHEMBL402064)
Show SMILES CS(=O)(=O)c1ccccc1-c1ccc(N2CCCC(NS(=O)(=O)c3ccc(Cl)s3)C2=O)c(F)c1 |w:18.19|
Show InChI InChI=1S/C22H20ClFN2O5S3/c1-33(28,29)19-7-3-2-5-15(19)14-8-9-18(16(24)13-14)26-12-4-6-17(22(26)27)25-34(30,31)21-11-10-20(23)32-21/h2-3,5,7-11,13,17,25H,4,6,12H2,1H3
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 5.30n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a

Bioorg Med Chem Lett 18: 2428-33 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.054
BindingDB Entry DOI: 10.7270/Q2RX9CZ8
More data for this
Ligand-Target Pair