BDBM50374919 CHEMBL272116

SMILES: CS(=O)(=O)c1ccccc1-c1ccc(N2CCCC(NS(=O)(=O)c3ccc(F)c(F)c3)C2=O)c(F)c1

InChI Key: InChIKey=CSMAVHWEKRXHDF-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50374919   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50374919 (CHEMBL272116) Show SMILES CS(=O)(=O)c1ccccc1-c1ccc(N2CCCC(NS(=O)(=O)c3ccc(F)c(F)c3)C2=O)c(F)c1 |w:18.19| Show InChI InChI=1S/C24H21F3N2O5S2/c1-35(31,32)23-7-3-2-5-17(23)15-8-11-22(20(27)13-15)29-12-4-6-21(24(29)30)28-36(33,34)16-9-10-18(25)19(26)14-16/h2-3,5,7-11,13-14,21,28H,4,6,12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human factor 10a				Bioorg Med Chem Lett 18: 2428-33 (2008) Article DOI: 10.1016/j.bmcl.2008.02.054 BindingDB Entry DOI: 10.7270/Q2RX9CZ8
					More data for this Ligand-Target Pair