BDBM50374920 CHEMBL257241

SMILES: CS(=O)(=O)c1ccccc1-c1ccc(N2CCCC(NS(=O)(=O)c3ccc(cc3)C#N)C2=O)c(F)c1

InChI Key: InChIKey=WNGWEQRQWBLSSB-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50374920   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50374920 (CHEMBL257241) Show SMILES CS(=O)(=O)c1ccccc1-c1ccc(N2CCCC(NS(=O)(=O)c3ccc(cc3)C#N)C2=O)c(F)c1 |w:18.19| Show InChI InChI=1S/C25H22FN3O5S2/c1-35(31,32)24-7-3-2-5-20(24)18-10-13-23(21(26)15-18)29-14-4-6-22(25(29)30)28-36(33,34)19-11-8-17(16-27)9-12-19/h2-3,5,7-13,15,22,28H,4,6,14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human factor 10a				Bioorg Med Chem Lett 18: 2428-33 (2008) Article DOI: 10.1016/j.bmcl.2008.02.054 BindingDB Entry DOI: 10.7270/Q2RX9CZ8
					More data for this Ligand-Target Pair