BDBM50375134 PTERIDINONE

SMILES: CCOC(=O)c1nc2cnc(Nc3ccccc3)nc2n(-c2ccccc2)c1=O

InChI Key: InChIKey=CIZZUEUKGNBQPP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50375134   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony stimulating factor receptor (Homo sapiens (Human))	BDBM50375134 (PTERIDINONE) Show SMILES CCOC(=O)c1nc2cnc(Nc3ccccc3)nc2n(-c2ccccc2)c1=O Show InChI InChI=1S/C21H17N5O3/c1-2-29-20(28)17-19(27)26(15-11-7-4-8-12-15)18-16(24-17)13-22-21(25-18)23-14-9-5-3-6-10-14/h3-13H,2H2,1H3,(H,22,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of CSF1R				Bioorg Med Chem Lett 18: 2355-61 (2008) Article DOI: 10.1016/j.bmcl.2008.02.070 BindingDB Entry DOI: 10.7270/Q26W9BX3
					More data for this Ligand-Target Pair