BDBM50375137 CHEMBL272773

SMILES: NC(=O)c1cn(-c2ccc3CCCc3c2)c2nc(NCCN3CCOCC3)ncc2c1=O

InChI Key: InChIKey=DPUGIFATYUPFRA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50375137   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony stimulating factor receptor (Homo sapiens (Human))	BDBM50375137 (CHEMBL272773) Show SMILES NC(=O)c1cn(-c2ccc3CCCc3c2)c2nc(NCCN3CCOCC3)ncc2c1=O Show InChI InChI=1S/C23H26N6O3/c24-21(31)19-14-29(17-5-4-15-2-1-3-16(15)12-17)22-18(20(19)30)13-26-23(27-22)25-6-7-28-8-10-32-11-9-28/h4-5,12-14H,1-3,6-11H2,(H2,24,31)(H,25,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of ATP-induced CSF1R autophosphorylation				Bioorg Med Chem Lett 18: 2355-61 (2008) Article DOI: 10.1016/j.bmcl.2008.02.070 BindingDB Entry DOI: 10.7270/Q26W9BX3
					More data for this Ligand-Target Pair