BDBM50375145 CHEMBL271461
SMILES: NC(=O)c1cn(-c2ccc3CCCc3c2)c2nc(Nc3ccc(cc3)N3CCNCC3)ncc2c1=O
InChI Key: InChIKey=KQKRVYHUGXKQRH-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Macrophage colony stimulating factor receptor (Homo sapiens (Human)) | BDBM50375145 (CHEMBL271461) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL | Assay Description Inhibition of ATP-induced CSF1R autophosphorylation | Bioorg Med Chem Lett 18: 2355-61 (2008) Article DOI: 10.1016/j.bmcl.2008.02.070 BindingDB Entry DOI: 10.7270/Q26W9BX3 | |||||||||||
More data for this Ligand-Target Pair |