BDBM50375145 CHEMBL271461

SMILES: NC(=O)c1cn(-c2ccc3CCCc3c2)c2nc(Nc3ccc(cc3)N3CCNCC3)ncc2c1=O

InChI Key: InChIKey=KQKRVYHUGXKQRH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50375145   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony stimulating factor receptor (Homo sapiens (Human))	BDBM50375145 (CHEMBL271461) Show SMILES NC(=O)c1cn(-c2ccc3CCCc3c2)c2nc(Nc3ccc(cc3)N3CCNCC3)ncc2c1=O Show InChI InChI=1S/C27H27N7O2/c28-25(36)23-16-34(21-7-4-17-2-1-3-18(17)14-21)26-22(24(23)35)15-30-27(32-26)31-19-5-8-20(9-6-19)33-12-10-29-11-13-33/h4-9,14-16,29H,1-3,10-13H2,(H2,28,36)(H,30,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of ATP-induced CSF1R autophosphorylation				Bioorg Med Chem Lett 18: 2355-61 (2008) Article DOI: 10.1016/j.bmcl.2008.02.070 BindingDB Entry DOI: 10.7270/Q26W9BX3
					More data for this Ligand-Target Pair