BDBM50375156 CHEMBL273194

SMILES: CCOC(=O)c1cn(-c2ccc3CCCc3c2)c2nc(Nc3ccc(cc3)N3CCN(C)CC3)ncc2c1=O

InChI Key: InChIKey=XCJIUNJTUIGAPW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50375156   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony stimulating factor receptor (Homo sapiens (Human))	BDBM50375156 (CHEMBL273194) Show SMILES CCOC(=O)c1cn(-c2ccc3CCCc3c2)c2nc(Nc3ccc(cc3)N3CCN(C)CC3)ncc2c1=O Show InChI InChI=1S/C30H32N6O3/c1-3-39-29(38)26-19-36(24-10-7-20-5-4-6-21(20)17-24)28-25(27(26)37)18-31-30(33-28)32-22-8-11-23(12-9-22)35-15-13-34(2)14-16-35/h7-12,17-19H,3-6,13-16H2,1-2H3,(H,31,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of ATP-induced CSF1R autophosphorylation				Bioorg Med Chem Lett 18: 2355-61 (2008) Article DOI: 10.1016/j.bmcl.2008.02.070 BindingDB Entry DOI: 10.7270/Q26W9BX3
					More data for this Ligand-Target Pair