BDBM50375196 CHEMBL402531

SMILES: CCn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C(=O)c1cccs1

InChI Key: InChIKey=IDMQVBIPKRZHML-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50375196   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50375196 (CHEMBL402531) Show SMILES CCn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C(=O)c1cccs1 Show InChI InChI=1S/C27H22N4O2S/c1-3-31-20-9-6-14(26(32)21-5-4-10-34-21)11-16(20)23-17-12-28-27(33)24(17)22-15(25(23)31)7-8-19-18(22)13-30(2)29-19/h4-6,9-11,13H,3,7-8,12H2,1-2H3,(H,28,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 18: 2368-72 (2008) Article DOI: 10.1016/j.bmcl.2008.02.069 BindingDB Entry DOI: 10.7270/Q2ZG6T3P
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50375196 (CHEMBL402531) Show SMILES CCn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C(=O)c1cccs1 Show InChI InChI=1S/C27H22N4O2S/c1-3-31-20-9-6-14(26(32)21-5-4-10-34-21)11-16(20)23-17-12-28-27(33)24(17)22-15(25(23)31)7-8-19-18(22)13-30(2)29-19/h4-6,9-11,13H,3,7-8,12H2,1-2H3,(H,28,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of TIE2				Bioorg Med Chem Lett 18: 2368-72 (2008) Article DOI: 10.1016/j.bmcl.2008.02.069 BindingDB Entry DOI: 10.7270/Q2ZG6T3P
					More data for this Ligand-Target Pair