Found 5 hits for monomerid = 50375676 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50375676
(CHEMBL272875)Show SMILES CCNC(=O)N1CCOc2cc(Oc3ccnc4cc(OC)c(OC)cc34)ccc12 Show InChI InChI=1S/C22H23N3O5/c1-4-23-22(26)25-9-10-29-19-11-14(5-6-17(19)25)30-18-7-8-24-16-13-21(28-3)20(27-2)12-15(16)18/h5-8,11-13H,4,9-10H2,1-3H3,(H,23,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of KDR by HTRF assay |
J Med Chem 51: 1695-705 (2008)
Article DOI: 10.1021/jm701129j
BindingDB Entry DOI: 10.7270/Q28K79ZW |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase Lck
(Homo sapiens (Human)) | BDBM50375676
(CHEMBL272875)Show SMILES CCNC(=O)N1CCOc2cc(Oc3ccnc4cc(OC)c(OC)cc34)ccc12 Show InChI InChI=1S/C22H23N3O5/c1-4-23-22(26)25-9-10-29-19-11-14(5-6-17(19)25)30-18-7-8-24-16-13-21(28-3)20(27-2)12-15(16)18/h5-8,11-13H,4,9-10H2,1-3H3,(H,23,26) | PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of Lck |
J Med Chem 51: 1695-705 (2008)
Article DOI: 10.1021/jm701129j
BindingDB Entry DOI: 10.7270/Q28K79ZW |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50375676
(CHEMBL272875)Show SMILES CCNC(=O)N1CCOc2cc(Oc3ccnc4cc(OC)c(OC)cc34)ccc12 Show InChI InChI=1S/C22H23N3O5/c1-4-23-22(26)25-9-10-29-19-11-14(5-6-17(19)25)30-18-7-8-24-16-13-21(28-3)20(27-2)12-15(16)18/h5-8,11-13H,4,9-10H2,1-3H3,(H,23,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Lanzhou University
Curated by ChEMBL
| Assay Description
Inhibition of human VEGFR2 after 60 mins |
J Mol Graph Model 27: 642-54 (2008)
Article DOI: 10.1016/j.jmgm.2008.10.006
BindingDB Entry DOI: 10.7270/Q2C24XNX |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50375676
(CHEMBL272875)Show SMILES CCNC(=O)N1CCOc2cc(Oc3ccnc4cc(OC)c(OC)cc34)ccc12 Show InChI InChI=1S/C22H23N3O5/c1-4-23-22(26)25-9-10-29-19-11-14(5-6-17(19)25)30-18-7-8-24-16-13-21(28-3)20(27-2)12-15(16)18/h5-8,11-13H,4,9-10H2,1-3H3,(H,23,26) | PDB
MMDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of c-Met |
J Med Chem 51: 1695-705 (2008)
Article DOI: 10.1021/jm701129j
BindingDB Entry DOI: 10.7270/Q28K79ZW |
More data for this
Ligand-Target Pair | |
Angiopoietin-1 receptor
(Homo sapiens (Human)) | BDBM50375676
(CHEMBL272875)Show SMILES CCNC(=O)N1CCOc2cc(Oc3ccnc4cc(OC)c(OC)cc34)ccc12 Show InChI InChI=1S/C22H23N3O5/c1-4-23-22(26)25-9-10-29-19-11-14(5-6-17(19)25)30-18-7-8-24-16-13-21(28-3)20(27-2)12-15(16)18/h5-8,11-13H,4,9-10H2,1-3H3,(H,23,26) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of Tie2 |
J Med Chem 51: 1695-705 (2008)
Article DOI: 10.1021/jm701129j
BindingDB Entry DOI: 10.7270/Q28K79ZW |
More data for this
Ligand-Target Pair | |
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