BDBM50375825 CHEMBL406235

SMILES: Cn1c(ccc1-c1cc2c(NC(=O)C2(C)C)cc1F)C#N

InChI Key: InChIKey=UWFRUEUBOYKJIU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50375825   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50375825 (CHEMBL406235) Show SMILES Cn1c(ccc1-c1cc2c(NC(=O)C2(C)C)cc1F)C#N Show InChI InChI=1S/C16H14FN3O/c1-16(2)11-6-10(12(17)7-13(11)19-15(16)21)14-5-4-9(8-18)20(14)3/h4-7H,1-3H3,(H,19,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20.3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair