BDBM50375840 CHEMBL405428

SMILES: CCN1C(=O)C(C)(C)c2cc(cc(F)c12)-c1ccc(C#N)n1C

InChI Key: InChIKey=BNGOGZNXYPKZAN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50375840   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50375840 (CHEMBL405428) Show SMILES CCN1C(=O)C(C)(C)c2cc(cc(F)c12)-c1ccc(C#N)n1C Show InChI InChI=1S/C18H18FN3O/c1-5-22-16-13(18(2,3)17(22)23)8-11(9-14(16)19)15-7-6-12(10-20)21(15)4/h6-9H,5H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair