BDBM50375853 CHEMBL410064

SMILES: [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]/[#6]C([#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])(P([#8])([#8])=O)P([#8])([#8])=O

InChI Key: InChIKey=CURJGMZOEBUTAS-ZLIRQAPQSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50375853   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Geranylgeranyl Diphosphate Synthase (GGPPS) (Homo sapiens (Human))	BDBM50375853 (CHEMBL410064) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]/[#6]C([#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])(P([#8])([#8])=O)P([#8])([#8])=O Show InChI InChI=1S/C26H46O6P2/c1-21(2)11-8-13-23(5)15-10-16-25(7)18-20-26(33(27,28)29,34(30,31)32)19-17-24(6)14-9-12-22(3)4/h11-12,15,17-18H,8-10,13-14,16,19-20H2,1-7H3,(H2,27,28,29)(H2,30,31,32)/b23-15+,24-17+,25-18-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of Iowa Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant GGDPS expressed in BL21 gold bacteria				Bioorg Med Chem 16: 390-9 (2008) Article DOI: 10.1016/j.bmc.2007.09.029 BindingDB Entry DOI: 10.7270/Q26M37PP
					More data for this Ligand-Target Pair