BDBM50376018 CHEMBL270745

SMILES: COc1cc2nccc(Oc3ccc4c(ccnc4c3)C(=O)Nc3ccc(Cl)cc3)c2cc1OC

InChI Key: InChIKey=RRBXHERNTPHTQX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50376018   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50376018 (CHEMBL270745) Show SMILES COc1cc2nccc(Oc3ccc4c(ccnc4c3)C(=O)Nc3ccc(Cl)cc3)c2cc1OC Show InChI InChI=1S/C27H20ClN3O4/c1-33-25-14-21-23(15-26(25)34-2)30-12-10-24(21)35-18-7-8-19-20(9-11-29-22(19)13-18)27(32)31-17-5-3-16(28)4-6-17/h3-15H,1-2H3,(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21.9	n/a	n/a	n/a	n/a	n/a	n/a
Lanzhou University Curated by ChEMBL					Assay Description Inhibition of human VEGFR2 after 60 mins				J Mol Graph Model 27: 642-54 (2008) Article DOI: 10.1016/j.jmgm.2008.10.006 BindingDB Entry DOI: 10.7270/Q2C24XNX
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50376018 (CHEMBL270745) Show SMILES COc1cc2nccc(Oc3ccc4c(ccnc4c3)C(=O)Nc3ccc(Cl)cc3)c2cc1OC Show InChI InChI=1S/C27H20ClN3O4/c1-33-25-14-21-23(15-26(25)34-2)30-12-10-24(21)35-18-7-8-19-20(9-11-29-22(19)13-18)27(32)31-17-5-3-16(28)4-6-17/h3-15H,1-2H3,(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of KDR by HTRF assay				J Med Chem 51: 1649-67 (2008) Article DOI: 10.1021/jm701097z BindingDB Entry DOI: 10.7270/Q29C6Z8N
					More data for this Ligand-Target Pair