BDBM50376023 CHEMBL408478
SMILES: COc1cc2nccc(Oc3ccc4c(cccc4c3)C(=O)Nc3cc(on3)C(C)(C)C)c2cc1OC
InChI Key: InChIKey=ZWQPZFHCKLZVGB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50376023 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50376023
(CHEMBL408478)Show SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(=O)Nc3cc(on3)C(C)(C)C)c2cc1OC Show InChI InChI=1S/C29H27N3O5/c1-29(2,3)26-16-27(32-37-26)31-28(33)20-8-6-7-17-13-18(9-10-19(17)20)36-23-11-12-30-22-15-25(35-5)24(34-4)14-21(22)23/h6-16H,1-5H3,(H,31,32,33) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.794 | n/a | n/a | n/a | n/a | n/a | n/a |
Lanzhou University
Curated by ChEMBL
| Assay Description
Inhibition of human VEGFR2 after 60 mins |
J Mol Graph Model 27: 642-54 (2008)
Article DOI: 10.1016/j.jmgm.2008.10.006
BindingDB Entry DOI: 10.7270/Q2C24XNX |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50376023
(CHEMBL408478)Show SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(=O)Nc3cc(on3)C(C)(C)C)c2cc1OC Show InChI InChI=1S/C29H27N3O5/c1-29(2,3)26-16-27(32-37-26)31-28(33)20-8-6-7-17-13-18(9-10-19(17)20)36-23-11-12-30-22-15-25(35-5)24(34-4)14-21(22)23/h6-16H,1-5H3,(H,31,32,33) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of KDR by HTRF assay |
J Med Chem 51: 1649-67 (2008)
Article DOI: 10.1021/jm701097z
BindingDB Entry DOI: 10.7270/Q29C6Z8N |
More data for this
Ligand-Target Pair | |
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