BDBM50376051 CHEMBL269891

SMILES: Clc1ccc(NC(=O)c2cccc3cc(Oc4ccncc4)ccc23)cc1

InChI Key: InChIKey=QJPWZEVJMJTSRW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50376051   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50376051 (CHEMBL269891) Show SMILES Clc1ccc(NC(=O)c2cccc3cc(Oc4ccncc4)ccc23)cc1 Show InChI InChI=1S/C22H15ClN2O2/c23-16-4-6-17(7-5-16)25-22(26)21-3-1-2-15-14-19(8-9-20(15)21)27-18-10-12-24-13-11-18/h1-14H,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18.2	n/a	n/a	n/a	n/a	n/a	n/a
Lanzhou University Curated by ChEMBL					Assay Description Inhibition of human VEGFR2 after 60 mins				J Mol Graph Model 27: 642-54 (2008) Article DOI: 10.1016/j.jmgm.2008.10.006 BindingDB Entry DOI: 10.7270/Q2C24XNX
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50376051 (CHEMBL269891) Show SMILES Clc1ccc(NC(=O)c2cccc3cc(Oc4ccncc4)ccc23)cc1 Show InChI InChI=1S/C22H15ClN2O2/c23-16-4-6-17(7-5-16)25-22(26)21-3-1-2-15-14-19(8-9-20(15)21)27-18-10-12-24-13-11-18/h1-14H,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of KDR by HTRF assay				J Med Chem 51: 1649-67 (2008) Article DOI: 10.1021/jm701097z BindingDB Entry DOI: 10.7270/Q29C6Z8N
					More data for this Ligand-Target Pair