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SMILES: NC1(Cc2ccc(Cl)cc2)CCN(CC1)c1ncnc2nc[nH]c12

InChI Key: InChIKey=JFEKXAZDKRLRSO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50376058   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RAC-beta serine/threonine-protein kinase


(Homo sapiens (Human))		BDBM50376058
PNG
(CHEMBL259999)
Show SMILES NC1(Cc2ccc(Cl)cc2)CCN(CC1)c1ncnc2nc[nH]c12
Show InChI InChI=1S/C17H19ClN6/c18-13-3-1-12(2-4-13)9-17(19)5-7-24(8-6-17)16-14-15(21-10-20-14)22-11-23-16/h1-4,10-11H,5-9,19H2,(H,20,21,22,23)
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 25n/an/an/an/an/an/a



The Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of PKBbeta recombinant by radiometric filter binding assay

J Med Chem 51: 2147-57 (2008)


Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8
More data for this
Ligand-Target Pair