BDBM50376069 CHEMBL405384

SMILES: NC(C1CCN(CC1)c1ncnc2[nH]ccc12)c1ccc(Cl)cc1

InChI Key: InChIKey=CUQIEUIMKDNKMI-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50376069   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50376069 (CHEMBL405384) Show SMILES NC(C1CCN(CC1)c1ncnc2[nH]ccc12)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H20ClN5/c19-14-3-1-12(2-4-14)16(20)13-6-9-24(10-7-13)18-15-5-8-21-17(15)22-11-23-18/h1-5,8,11,13,16H,6-7,9-10,20H2,(H,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GSK3-beta in human PC3M cells by ELISA				J Med Chem 51: 2147-57 (2008) Article DOI: 10.1021/jm701437d BindingDB Entry DOI: 10.7270/Q2X63NV8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase AKT2 (Homo sapiens (Human))	BDBM50376069 (CHEMBL405384) Show SMILES NC(C1CCN(CC1)c1ncnc2[nH]ccc12)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H20ClN5/c19-14-3-1-12(2-4-14)16(20)13-6-9-24(10-7-13)18-15-5-8-21-17(15)22-11-23-18/h1-5,8,11,13,16H,6-7,9-10,20H2,(H,21,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of PKBbeta recombinant by radiometric filter binding assay				J Med Chem 51: 2147-57 (2008) Article DOI: 10.1021/jm701437d BindingDB Entry DOI: 10.7270/Q2X63NV8
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50376069 (CHEMBL405384) Show SMILES NC(C1CCN(CC1)c1ncnc2[nH]ccc12)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H20ClN5/c19-14-3-1-12(2-4-14)16(20)13-6-9-24(10-7-13)18-15-5-8-21-17(15)22-11-23-18/h1-5,8,11,13,16H,6-7,9-10,20H2,(H,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GSK3-beta in human PC3M cells by ELISA				J Med Chem 51: 2147-57 (2008) Article DOI: 10.1021/jm701437d BindingDB Entry DOI: 10.7270/Q2X63NV8
					More data for this Ligand-Target Pair