BDBM50376479 CHEMBL261081

SMILES: Fc1ccc(F)c(c1)-c1ccc2N=C(CC(=O)Nc2c1)c1cccc(c1)-n1ccnn1

InChI Key: InChIKey=ZJLGPONIPOFEKB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50376479   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50376479 (CHEMBL261081) Show SMILES Fc1ccc(F)c(c1)-c1ccc2N=C(CC(=O)Nc2c1)c1cccc(c1)-n1ccnn1 |c:13| Show InChI InChI=1S/C23H15F2N5O/c24-16-5-6-19(25)18(12-16)14-4-7-20-22(11-14)28-23(31)13-21(27-20)15-2-1-3-17(10-15)30-9-8-26-29-30/h1-12H,13H2,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR2 assessed as blockade of (1S,3R)-ACPD-induced inhibition of forskolin-stimulated cAMP production				Bioorg Med Chem Lett 18: 2725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.02.076 BindingDB Entry DOI: 10.7270/Q2S75H7D
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50376479 (CHEMBL261081) Show SMILES Fc1ccc(F)c(c1)-c1ccc2N=C(CC(=O)Nc2c1)c1cccc(c1)-n1ccnn1 |c:13| Show InChI InChI=1S/C23H15F2N5O/c24-16-5-6-19(25)18(12-16)14-4-7-20-22(11-14)28-23(31)13-21(27-20)15-2-1-3-17(10-15)30-9-8-26-29-30/h1-12H,13H2,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]LY354740 from rat mGluR2				Bioorg Med Chem Lett 18: 2725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.02.076 BindingDB Entry DOI: 10.7270/Q2S75H7D
					More data for this Ligand-Target Pair