BDBM50376798 CHEMBL407004

SMILES: CCN(C1CCCc2nc(Cl)cc(OC)c12)c1cccc2ccccc12

InChI Key: InChIKey=PFWXTNUVYDWTEH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50376798   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM50376798 (CHEMBL407004) Show SMILES CCN(C1CCCc2nc(Cl)cc(OC)c12)c1cccc2ccccc12 |w:3.2| Show InChI InChI=1S/C22H23ClN2O/c1-3-25(18-12-6-9-15-8-4-5-10-16(15)18)19-13-7-11-17-22(19)20(26-2)14-21(23)24-17/h4-6,8-10,12,14,19H,3,7,11,13H2,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson PRD Curated by ChEMBL					Assay Description Antagonist activity at human C5a receptor in U937 cells assessed as inhibition of anaphylatoxin-induced intracellular calcium mobilization				Bioorg Med Chem Lett 18: 2544-8 (2008) Article DOI: 10.1016/j.bmcl.2008.03.049 BindingDB Entry DOI: 10.7270/Q2JM2BHD
					More data for this Ligand-Target Pair