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BDBM50376814 CHEMBL260472

SMILES: CCc1cccc(CC)c1-c1cc(OC)c2C(CCCc2n1)N(C(C)=O)c1cccc2ccccc12

InChI Key: InChIKey=OUEVRLOQDLFPIU-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50376814   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C5a anaphylatoxin chemotactic receptor (C5aR)


(Homo sapiens (Human))		BDBM50376814
PNG
(CHEMBL260472)
Show SMILES CCc1cccc(CC)c1-c1cc(OC)c2C(CCCc2n1)N(C(C)=O)c1cccc2ccccc12 |w:16.24|
Show InChI InChI=1S/C32H34N2O2/c1-5-22-13-9-14-23(6-2)31(22)27-20-30(36-4)32-26(33-27)17-11-19-29(32)34(21(3)35)28-18-10-15-24-12-7-8-16-25(24)28/h7-10,12-16,18,20,29H,5-6,11,17,19H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 6.20E+3n/an/an/an/an/an/a



Johnson& Johnson PRD

Curated by ChEMBL


Assay Description
Antagonist activity at human C5a receptor in U937 cells assessed as inhibition of anaphylatoxin-induced intracellular calcium mobilization

Bioorg Med Chem Lett 18: 2544-8 (2008)


Article DOI: 10.1016/j.bmcl.2008.03.049
BindingDB Entry DOI: 10.7270/Q2JM2BHD
More data for this
Ligand-Target Pair