BDBM50376820 CHEMBL259970

SMILES: CCc1cccc(CC)c1-c1cc(OC)c2C(CCCc2n1)N(C)c1ccc2ccccc2c1

InChI Key: InChIKey=GFMFLTMFBXRFAL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50376820   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM50376820 (CHEMBL259970) Show SMILES CCc1cccc(CC)c1-c1cc(OC)c2C(CCCc2n1)N(C)c1ccc2ccccc2c1 |w:16.24| Show InChI InChI=1S/C31H34N2O/c1-5-21-13-9-14-22(6-2)30(21)27-20-29(34-4)31-26(32-27)15-10-16-28(31)33(3)25-18-17-23-11-7-8-12-24(23)19-25/h7-9,11-14,17-20,28H,5-6,10,15-16H2,1-4H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson PRD Curated by ChEMBL					Assay Description Antagonist activity at human C5a receptor in U937 cells assessed as inhibition of anaphylatoxin-induced intracellular calcium mobilization				Bioorg Med Chem Lett 18: 2544-8 (2008) Article DOI: 10.1016/j.bmcl.2008.03.049 BindingDB Entry DOI: 10.7270/Q2JM2BHD
					More data for this Ligand-Target Pair