Found 6 hits for monomerid = 50376853 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Prostaglandin G/H synthase (cyclooxygenase)
(Ovis aries (Sheep)) | BDBM50376853
(CHEMBL258986)Show SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2ccccc12)C(F)(F)F |c:12| Show InChI InChI=1S/C18H15F3N4O2S/c19-18(20,21)17-9-16(14-10-23-15-4-2-1-3-13(14)15)25(24-17)11-5-7-12(8-6-11)28(22,26)27/h1-8,10,16,23H,9H2,(H2,22,26,27) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University School of Medicine
Curated by ChEMBL
| Assay Description
Inhibition of ovine COX1 by enzyme immuno assay |
Bioorg Med Chem 16: 3907-16 (2008)
Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4 |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase (Cyclooxygenase-2)
(Ovis aries (Sheep)) | BDBM50376853
(CHEMBL258986)Show SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2ccccc12)C(F)(F)F |c:12| Show InChI InChI=1S/C18H15F3N4O2S/c19-18(20,21)17-9-16(14-10-23-15-4-2-1-3-13(14)15)25(24-17)11-5-7-12(8-6-11)28(22,26)27/h1-8,10,16,23H,9H2,(H2,22,26,27) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University School of Medicine
Curated by ChEMBL
| Assay Description
Inhibition of ovine COX2 by enzyme immuno assay |
Bioorg Med Chem 16: 3907-16 (2008)
Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4 |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase (Cyclooxygenase-2)
(Ovis aries (Sheep)) | BDBM50376853
(CHEMBL258986)Show SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2ccccc12)C(F)(F)F |c:12| Show InChI InChI=1S/C18H15F3N4O2S/c19-18(20,21)17-9-16(14-10-23-15-4-2-1-3-13(14)15)25(24-17)11-5-7-12(8-6-11)28(22,26)27/h1-8,10,16,23H,9H2,(H2,22,26,27) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University School of Medicine
Curated by ChEMBL
| Assay Description
Inhibition of ovine COX2 by enzyme immuno assay |
Bioorg Med Chem 16: 3907-16 (2008)
Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4 |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase (cyclooxygenase)
(Ovis aries (Sheep)) | BDBM50376853
(CHEMBL258986)Show SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2ccccc12)C(F)(F)F |c:12| Show InChI InChI=1S/C18H15F3N4O2S/c19-18(20,21)17-9-16(14-10-23-15-4-2-1-3-13(14)15)25(24-17)11-5-7-12(8-6-11)28(22,26)27/h1-8,10,16,23H,9H2,(H2,22,26,27) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University School of Medicine
Curated by ChEMBL
| Assay Description
Inhibition of ovine COX1 by enzyme immuno assay |
Bioorg Med Chem 16: 3907-16 (2008)
Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4 |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase (Cyclooxygenase-2)
(Ovis aries (Sheep)) | BDBM50376853
(CHEMBL258986)Show SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2ccccc12)C(F)(F)F |c:12| Show InChI InChI=1S/C18H15F3N4O2S/c19-18(20,21)17-9-16(14-10-23-15-4-2-1-3-13(14)15)25(24-17)11-5-7-12(8-6-11)28(22,26)27/h1-8,10,16,23H,9H2,(H2,22,26,27) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 850 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University School of Medicine
Curated by ChEMBL
| Assay Description
Inhibition of ovine COX2 by enzyme immuno assay |
Bioorg Med Chem 16: 3907-16 (2008)
Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4 |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase (cyclooxygenase)
(Ovis aries (Sheep)) | BDBM50376853
(CHEMBL258986)Show SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2ccccc12)C(F)(F)F |c:12| Show InChI InChI=1S/C18H15F3N4O2S/c19-18(20,21)17-9-16(14-10-23-15-4-2-1-3-13(14)15)25(24-17)11-5-7-12(8-6-11)28(22,26)27/h1-8,10,16,23H,9H2,(H2,22,26,27) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University School of Medicine
Curated by ChEMBL
| Assay Description
Inhibition of ovine COX1 by enzyme immuno assay |
Bioorg Med Chem 16: 3907-16 (2008)
Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4 |
More data for this
Ligand-Target Pair | |
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