BDBM50377130 CHEMBL256523

SMILES: O=S(=O)(N1CCCC1)c1ccc(cc1)-c1ccnc(Nc2ccc3ncsc3c2)n1

InChI Key: InChIKey=LLDHJKGIKOSILY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50377130   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inhibitor of nuclear factor kappa-B kinase subunit beta (Homo sapiens (Human))	BDBM50377130 (CHEMBL256523) Show SMILES O=S(=O)(N1CCCC1)c1ccc(cc1)-c1ccnc(Nc2ccc3ncsc3c2)n1 Show InChI InChI=1S/C21H19N5O2S2/c27-30(28,26-11-1-2-12-26)17-6-3-15(4-7-17)18-9-10-22-21(25-18)24-16-5-8-19-20(13-16)29-14-23-19/h3-10,13-14H,1-2,11-12H2,(H,22,24,25)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
UCB Curated by ChEMBL					Assay Description Inhibition of IKK2				Bioorg Med Chem Lett 18: 3622-7 (2008) Article DOI: 10.1016/j.bmcl.2008.04.062 BindingDB Entry DOI: 10.7270/Q2P55PD3
					More data for this Ligand-Target Pair