BDBM50377146 CHEMBL428424

SMILES: N(c1ccc2ncsc2c1)c1nccc(n1)-c1ccc(cc1)-n1ccnc1

InChI Key: InChIKey=DOZSFMCFKIVLPU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50377146   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inhibitor of nuclear factor kappa-B kinase subunit beta (Homo sapiens (Human))	BDBM50377146 (CHEMBL428424) Show SMILES N(c1ccc2ncsc2c1)c1nccc(n1)-c1ccc(cc1)-n1ccnc1 Show InChI InChI=1S/C20H14N6S/c1-4-16(26-10-9-21-12-26)5-2-14(1)17-7-8-22-20(25-17)24-15-3-6-18-19(11-15)27-13-23-18/h1-13H,(H,22,24,25)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
UCB Curated by ChEMBL					Assay Description Inhibition of IKK2				Bioorg Med Chem Lett 18: 3622-7 (2008) Article DOI: 10.1016/j.bmcl.2008.04.062 BindingDB Entry DOI: 10.7270/Q2P55PD3
					More data for this Ligand-Target Pair