BDBM50377269 CHEMBL402149

SMILES: CO\N=C\c1c(N)ncnc1Nc1cccc(Br)c1

InChI Key: InChIKey=OCXORRCMDXTOHV-UBKPWBPPSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50377269   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50377269 (CHEMBL402149) Show SMILES CO\N=C\c1c(N)ncnc1Nc1cccc(Br)c1 Show InChI InChI=1S/C12H12BrN5O/c1-19-17-6-10-11(14)15-7-16-12(10)18-9-4-2-3-8(13)5-9/h2-7H,1H3,(H3,14,15,16,18)/b17-6+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of EGFR				Bioorg Med Chem Lett 18: 3495-9 (2008) Article DOI: 10.1016/j.bmcl.2008.05.024 BindingDB Entry DOI: 10.7270/Q21G0N5V
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50377269 (CHEMBL402149) Show SMILES CO\N=C\c1c(N)ncnc1Nc1cccc(Br)c1 Show InChI InChI=1S/C12H12BrN5O/c1-19-17-6-10-11(14)15-7-16-12(10)18-9-4-2-3-8(13)5-9/h2-7H,1H3,(H3,14,15,16,18)/b17-6+	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	557	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of ErbB2				Bioorg Med Chem Lett 18: 3495-9 (2008) Article DOI: 10.1016/j.bmcl.2008.05.024 BindingDB Entry DOI: 10.7270/Q21G0N5V
					More data for this Ligand-Target Pair