BDBM50377288 CHEMBL402113
SMILES: CO\N=C\c1c(N)ncnc1Nc1ccc2n(Cc3ccccc3)ncc2c1
InChI Key: InChIKey=TUVKKBPRVDBWKZ-OPEKNORGSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50377288 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50377288
(CHEMBL402113)Show SMILES CO\N=C\c1c(N)ncnc1Nc1ccc2n(Cc3ccccc3)ncc2c1 Show InChI InChI=1S/C20H19N7O/c1-28-25-11-17-19(21)22-13-23-20(17)26-16-7-8-18-15(9-16)10-24-27(18)12-14-5-3-2-4-6-14/h2-11,13H,12H2,1H3,(H3,21,22,23,26)/b25-11+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development
Curated by ChEMBL
| Assay Description
Inhibition of EGFR |
Bioorg Med Chem Lett 18: 3495-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.024
BindingDB Entry DOI: 10.7270/Q21G0N5V |
More data for this
Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50377288
(CHEMBL402113)Show SMILES CO\N=C\c1c(N)ncnc1Nc1ccc2n(Cc3ccccc3)ncc2c1 Show InChI InChI=1S/C20H19N7O/c1-28-25-11-17-19(21)22-13-23-20(17)26-16-7-8-18-15(9-16)10-24-27(18)12-14-5-3-2-4-6-14/h2-11,13H,12H2,1H3,(H3,21,22,23,26)/b25-11+ | PDB
MMDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development
Curated by ChEMBL
| Assay Description
Inhibition of ErbB2 |
Bioorg Med Chem Lett 18: 3495-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.024
BindingDB Entry DOI: 10.7270/Q21G0N5V |
More data for this
Ligand-Target Pair | |
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