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SMILES: CC(C)c1c(cn2ncnc(Nc3cnc4[nH]c(C)cc4c3)c12)-c1nc(C)no1

InChI Key: InChIKey=DCORLGVOPVBDRF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50377358   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50377358
PNG
(CHEMBL258695)
Show SMILES CC(C)c1c(cn2ncnc(Nc3cnc4[nH]c(C)cc4c3)c12)-c1nc(C)no1
Show InChI InChI=1S/C20H20N8O/c1-10(2)16-15(20-25-12(4)27-29-20)8-28-17(16)19(22-9-23-28)26-14-6-13-5-11(3)24-18(13)21-7-14/h5-10H,1-4H3,(H,21,24)(H,22,23,26)
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MMDB

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Article
PubMed
n/an/a 113n/an/an/an/an/an/a



Bristol-Myers Squibb

Curated by ChEMBL


Assay Description
Inhibition of human VEGFR2

Bioorg Med Chem Lett 18: 2985-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.03.057
BindingDB Entry DOI: 10.7270/Q28053HZ
More data for this
Ligand-Target Pair