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SMILES: CC(C)c1c(cn2ncnc(Nc3cnc4[nH]ccc4c3)c12)-c1nc(C)no1

InChI Key: InChIKey=RSSKQOASPNWTBZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50377359   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50377359
PNG
(CHEMBL264943)
Show SMILES CC(C)c1c(cn2ncnc(Nc3cnc4[nH]ccc4c3)c12)-c1nc(C)no1
Show InChI InChI=1S/C19H18N8O/c1-10(2)15-14(19-24-11(3)26-28-19)8-27-16(15)18(22-9-23-27)25-13-6-12-4-5-20-17(12)21-7-13/h4-10H,1-3H3,(H,20,21)(H,22,23,25)
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n/an/a 96n/an/an/an/an/an/a



Bristol-Myers Squibb

Curated by ChEMBL


Assay Description
Inhibition of human VEGFR2

Bioorg Med Chem Lett 18: 2985-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.03.057
BindingDB Entry DOI: 10.7270/Q28053HZ
More data for this
Ligand-Target Pair