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SMILES: C[C@@H](O)COc1cn2ncnc(Nc3cnc4[nH]c(C)cc4c3)c2c1C

InChI Key: InChIKey=UFHZPQUCRBIJFF-LLVKDONJSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50377364   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50377364
PNG
(CHEMBL259996)
Show SMILES C[C@@H](O)COc1cn2ncnc(Nc3cnc4[nH]c(C)cc4c3)c2c1C
Show InChI InChI=1S/C18H20N6O2/c1-10-4-13-5-14(6-19-17(13)22-10)23-18-16-12(3)15(26-8-11(2)25)7-24(16)21-9-20-18/h4-7,9,11,25H,8H2,1-3H3,(H,19,22)(H,20,21,23)/t11-/m1/s1
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n/an/a 223n/an/an/an/an/an/a



Bristol-Myers Squibb

Curated by ChEMBL


Assay Description
Inhibition of human VEGFR2

Bioorg Med Chem Lett 18: 2985-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.03.057
BindingDB Entry DOI: 10.7270/Q28053HZ
More data for this
Ligand-Target Pair