BDBM50377601 CHEMBL259379

SMILES: NC(=S)NN=C(c1cccs1)c1cc(Cl)cc(Cl)c1

InChI Key: InChIKey=GLGCLPLEIOLAJV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50377601   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Procathepsin L (Homo sapiens (Human))	BDBM50377601 (CHEMBL259379) Show SMILES NC(=S)NN=C(c1cccs1)c1cc(Cl)cc(Cl)c1 |w:4.3| Show InChI InChI=1S/C12H9Cl2N3S2/c13-8-4-7(5-9(14)6-8)11(16-17-12(15)18)10-2-1-3-19-10/h1-6H,(H3,15,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human cathepsin L				Bioorg Med Chem Lett 18: 2883-5 (2008) Article DOI: 10.1016/j.bmcl.2008.03.083 BindingDB Entry DOI: 10.7270/Q2Q24150
					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50377601 (CHEMBL259379) Show SMILES NC(=S)NN=C(c1cccs1)c1cc(Cl)cc(Cl)c1 |w:4.3| Show InChI InChI=1S/C12H9Cl2N3S2/c13-8-4-7(5-9(14)6-8)11(16-17-12(15)18)10-2-1-3-19-10/h1-6H,(H3,15,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human cathepsin B				Bioorg Med Chem Lett 18: 2883-5 (2008) Article DOI: 10.1016/j.bmcl.2008.03.083 BindingDB Entry DOI: 10.7270/Q2Q24150
					More data for this Ligand-Target Pair