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BDBM50377639 CHEMBL258188

SMILES: Clc1ccc(NC(=O)c2cc(ccc2NC(=O)c2ccc(cc2)-n2ccccc2=O)C#N)nc1

InChI Key: InChIKey=DNNSLBMMINBAAK-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50377639   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50377639
PNG
(CHEMBL258188)
Show SMILES Clc1ccc(NC(=O)c2cc(ccc2NC(=O)c2ccc(cc2)-n2ccccc2=O)C#N)nc1
Show InChI InChI=1S/C25H16ClN5O3/c26-18-7-11-22(28-15-18)30-25(34)20-13-16(14-27)4-10-21(20)29-24(33)17-5-8-19(9-6-17)31-12-2-1-3-23(31)32/h1-13,15H,(H,29,33)(H,28,30,34)
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
2.20n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a


Bioorg Med Chem Lett 18: 2845-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.03.092
BindingDB Entry DOI: 10.7270/Q2611169
More data for this
Ligand-Target Pair