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BDBM50377652 CHEMBL256573

SMILES: Clc1ccc(NC(=O)c2ccccc2NCc2ccc(cc2)-n2ccccc2=O)nc1

InChI Key: InChIKey=HXFGOIVKTYTKDI-UHFFFAOYSA-N

Data: 1 KI

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50377652   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50377652
PNG
(CHEMBL256573)
Show SMILES Clc1ccc(NC(=O)c2ccccc2NCc2ccc(cc2)-n2ccccc2=O)nc1
Show InChI InChI=1S/C24H19ClN4O2/c25-18-10-13-22(27-16-18)28-24(31)20-5-1-2-6-21(20)26-15-17-8-11-19(12-9-17)29-14-4-3-7-23(29)30/h1-14,16,26H,15H2,(H,27,28,31)
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
1.10n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a


Bioorg Med Chem Lett 18: 2845-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.03.092
BindingDB Entry DOI: 10.7270/Q2611169
More data for this
Ligand-Target Pair