Found 4 hits for monomerid = 50377708 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50377708
(CHEMBL256752)Show SMILES CC1(C)[C@H]2CC[C@](C)(C2)[C@@H]1NC(=O)c1ccc(Br)c(c1)S(=O)(=O)N1CCCCC1 |THB:10:9:4.5:8| Show InChI InChI=1S/C22H31BrN2O3S/c1-21(2)16-9-10-22(3,14-16)20(21)24-19(26)15-7-8-17(23)18(13-15)29(27,28)25-11-5-4-6-12-25/h7-8,13,16,20H,4-6,9-12,14H2,1-3H3,(H,24,26)/t16-,20+,22+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Adolor Corporation
Curated by ChEMBL
| Assay Description Displacement of [3H]CP-55940 from human cloned CB2 receptor |
Bioorg Med Chem Lett 18: 2830-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.006 BindingDB Entry DOI: 10.7270/Q2P2701M |
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50377708
(CHEMBL256752)Show SMILES CC1(C)[C@H]2CC[C@](C)(C2)[C@@H]1NC(=O)c1ccc(Br)c(c1)S(=O)(=O)N1CCCCC1 |THB:10:9:4.5:8| Show InChI InChI=1S/C22H31BrN2O3S/c1-21(2)16-9-10-22(3,14-16)20(21)24-19(26)15-7-8-17(23)18(13-15)29(27,28)25-11-5-4-6-12-25/h7-8,13,16,20H,4-6,9-12,14H2,1-3H3,(H,24,26)/t16-,20+,22+/m0/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 93 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Adolor Corporation
Curated by ChEMBL
| Assay Description Displacement of [3H]CP-55940 from human cloned CB1 receptor |
Bioorg Med Chem Lett 18: 2830-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.006 BindingDB Entry DOI: 10.7270/Q2P2701M |
More data for this Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50377708
(CHEMBL256752)Show SMILES CC1(C)[C@H]2CC[C@](C)(C2)[C@@H]1NC(=O)c1ccc(Br)c(c1)S(=O)(=O)N1CCCCC1 |THB:10:9:4.5:8| Show InChI InChI=1S/C22H31BrN2O3S/c1-21(2)16-9-10-22(3,14-16)20(21)24-19(26)15-7-8-17(23)18(13-15)29(27,28)25-11-5-4-6-12-25/h7-8,13,16,20H,4-6,9-12,14H2,1-3H3,(H,24,26)/t16-,20+,22+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 6.60 | n/a | n/a | n/a | n/a |
Adolor Corporation
Curated by ChEMBL
| Assay Description Agonist activity at human cloned CB2 receptor by [35S]GTP-gamma-S binding assay |
Bioorg Med Chem Lett 18: 2830-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.006 BindingDB Entry DOI: 10.7270/Q2P2701M |
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50377708
(CHEMBL256752)Show SMILES CC1(C)[C@H]2CC[C@](C)(C2)[C@@H]1NC(=O)c1ccc(Br)c(c1)S(=O)(=O)N1CCCCC1 |THB:10:9:4.5:8| Show InChI InChI=1S/C22H31BrN2O3S/c1-21(2)16-9-10-22(3,14-16)20(21)24-19(26)15-7-8-17(23)18(13-15)29(27,28)25-11-5-4-6-12-25/h7-8,13,16,20H,4-6,9-12,14H2,1-3H3,(H,24,26)/t16-,20+,22+/m0/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 280 | n/a | n/a | n/a | n/a |
Adolor Corporation
Curated by ChEMBL
| Assay Description Agonist activity at human cloned CB1 receptor by [35S]GTPgammaS binding assay |
Bioorg Med Chem Lett 18: 2830-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.006 BindingDB Entry DOI: 10.7270/Q2P2701M |
More data for this Ligand-Target Pair | |