BDBM50377756 CHEMBL256298

SMILES: Cn1c(nnc1-c1ccccc1C(F)(F)F)-c1ccccc1Br

InChI Key: InChIKey=MBOZUGMFGFMJRX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50377756   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50377756 (CHEMBL256298) Show SMILES Cn1c(nnc1-c1ccccc1C(F)(F)F)-c1ccccc1Br Show InChI InChI=1S/C16H11BrF3N3/c1-23-14(10-6-2-4-8-12(10)16(18,19)20)21-22-15(23)11-7-3-5-9-13(11)17/h2-9H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells				Bioorg Med Chem Lett 18: 2799-804 (2008) Article DOI: 10.1016/j.bmcl.2008.04.010 BindingDB Entry DOI: 10.7270/Q2J9678F
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50377756 (CHEMBL256298) Show SMILES Cn1c(nnc1-c1ccccc1C(F)(F)F)-c1ccccc1Br Show InChI InChI=1S/C16H11BrF3N3/c1-23-14(10-6-2-4-8-12(10)16(18,19)20)21-22-15(23)11-7-3-5-9-13(11)17/h2-9H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells				Bioorg Med Chem Lett 18: 2799-804 (2008) Article DOI: 10.1016/j.bmcl.2008.04.010 BindingDB Entry DOI: 10.7270/Q2J9678F
					More data for this Ligand-Target Pair