BDBM50377875 CHEMBL256090

SMILES: Cc1ccc(cc1)C1(CCCCC1)c1nnc2CCCCCCn12

InChI Key: InChIKey=IMHUBBHLFGUOQY-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50377875   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50377875 (CHEMBL256090) Show SMILES Cc1ccc(cc1)C1(CCCCC1)c1nnc2CCCCCCn12 Show InChI InChI=1S/C21H29N3/c1-17-10-12-18(13-11-17)21(14-6-4-7-15-21)20-23-22-19-9-5-2-3-8-16-24(19)20/h10-13H,2-9,14-16H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human 11-beta-HSD1 by SPA assay				Bioorg Med Chem Lett 18: 3412-6 (2008) Article DOI: 10.1016/j.bmcl.2008.04.014 BindingDB Entry DOI: 10.7270/Q2H99625
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 2 (Homo sapiens (Human))	BDBM50377875 (CHEMBL256090) Show SMILES Cc1ccc(cc1)C1(CCCCC1)c1nnc2CCCCCCn12 Show InChI InChI=1S/C21H29N3/c1-17-10-12-18(13-11-17)21(14-6-4-7-15-21)20-23-22-19-9-5-2-3-8-16-24(19)20/h10-13H,2-9,14-16H2,1H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	216	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human 11-beta-HSD2 by SPA assay				Bioorg Med Chem Lett 18: 3412-6 (2008) Article DOI: 10.1016/j.bmcl.2008.04.014 BindingDB Entry DOI: 10.7270/Q2H99625
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50377875 (CHEMBL256090) Show SMILES Cc1ccc(cc1)C1(CCCCC1)c1nnc2CCCCCCn12 Show InChI InChI=1S/C21H29N3/c1-17-10-12-18(13-11-17)21(14-6-4-7-15-21)20-23-22-19-9-5-2-3-8-16-24(19)20/h10-13H,2-9,14-16H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	374	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of mouse 11-beta-HSD1 by SPA assay				Bioorg Med Chem Lett 18: 3412-6 (2008) Article DOI: 10.1016/j.bmcl.2008.04.014 BindingDB Entry DOI: 10.7270/Q2H99625
					More data for this Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2) (Mus musculus (mouse))	BDBM50377875 (CHEMBL256090) Show SMILES Cc1ccc(cc1)C1(CCCCC1)c1nnc2CCCCCCn12 Show InChI InChI=1S/C21H29N3/c1-17-10-12-18(13-11-17)21(14-6-4-7-15-21)20-23-22-19-9-5-2-3-8-16-24(19)20/h10-13H,2-9,14-16H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of mouse 11-beta-HSD2 by SPA assay				Bioorg Med Chem Lett 18: 3412-6 (2008) Article DOI: 10.1016/j.bmcl.2008.04.014 BindingDB Entry DOI: 10.7270/Q2H99625
					More data for this Ligand-Target Pair