BDBM50377881 CHEMBL256720

SMILES: Fc1ccccc1C1(CCC1)c1nnc2CCCCCCn12

InChI Key: InChIKey=JHVLIEDMRZFYKF-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50377881   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50377881 (CHEMBL256720) Show SMILES Fc1ccccc1C1(CCC1)c1nnc2CCCCCCn12 Show InChI InChI=1S/C18H22FN3/c19-15-9-5-4-8-14(15)18(11-7-12-18)17-21-20-16-10-3-1-2-6-13-22(16)17/h4-5,8-9H,1-3,6-7,10-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human 11-beta-HSD1 by SPA assay				Bioorg Med Chem Lett 18: 3412-6 (2008) Article DOI: 10.1016/j.bmcl.2008.04.014 BindingDB Entry DOI: 10.7270/Q2H99625
					More data for this Ligand-Target Pair
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2) (Mus musculus (mouse))	BDBM50377881 (CHEMBL256720) Show SMILES Fc1ccccc1C1(CCC1)c1nnc2CCCCCCn12 Show InChI InChI=1S/C18H22FN3/c19-15-9-5-4-8-14(15)18(11-7-12-18)17-21-20-16-10-3-1-2-6-13-22(16)17/h4-5,8-9H,1-3,6-7,10-13H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of mouse 11-beta-HSD2 by SPA assay				Bioorg Med Chem Lett 18: 3412-6 (2008) Article DOI: 10.1016/j.bmcl.2008.04.014 BindingDB Entry DOI: 10.7270/Q2H99625
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50377881 (CHEMBL256720) Show SMILES Fc1ccccc1C1(CCC1)c1nnc2CCCCCCn12 Show InChI InChI=1S/C18H22FN3/c19-15-9-5-4-8-14(15)18(11-7-12-18)17-21-20-16-10-3-1-2-6-13-22(16)17/h4-5,8-9H,1-3,6-7,10-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of mouse 11-beta-HSD1 by SPA assay				Bioorg Med Chem Lett 18: 3412-6 (2008) Article DOI: 10.1016/j.bmcl.2008.04.014 BindingDB Entry DOI: 10.7270/Q2H99625
					More data for this Ligand-Target Pair