null

SMILES: COc1cc(ccc1Nc1nc(Nc2ccsc2C(N)=O)c2cc[nH]c2n1)N1CCC(CC1)N1CCN(CC1)S(C)(=O)=O

InChI Key: InChIKey=BDOARDSSTXIEQY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50378024   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50378024 (CHEMBL1964269) Show SMILES COc1cc(ccc1Nc1nc(Nc2ccsc2C(N)=O)c2cc[nH]c2n1)N1CCC(CC1)N1CCN(CC1)S(C)(=O)=O Show InChI InChI=1S/C28H35N9O4S2/c1-41-23-17-19(35-10-6-18(7-11-35)36-12-14-37(15-13-36)43(2,39)40)3-4-21(23)32-28-33-26-20(5-9-30-26)27(34-28)31-22-8-16-42-24(22)25(29)38/h3-5,8-9,16-18H,6-7,10-15H2,1-2H3,(H2,29,38)(H3,30,31,32,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of IGF1R				Bioorg Med Chem Lett 19: 373-7 (2008) Article DOI: 10.1016/j.bmcl.2008.11.065 BindingDB Entry DOI: 10.7270/Q2F190PC
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50378024 (CHEMBL1964269) Show SMILES COc1cc(ccc1Nc1nc(Nc2ccsc2C(N)=O)c2cc[nH]c2n1)N1CCC(CC1)N1CCN(CC1)S(C)(=O)=O Show InChI InChI=1S/C28H35N9O4S2/c1-41-23-17-19(35-10-6-18(7-11-35)36-12-14-37(15-13-36)43(2,39)40)3-4-21(23)32-28-33-26-20(5-9-30-26)27(34-28)31-22-8-16-42-24(22)25(29)38/h3-5,8-9,16-18H,6-7,10-15H2,1-2H3,(H2,29,38)(H3,30,31,32,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of IGF1R phosphorylation by cellular assay				Bioorg Med Chem Lett 19: 373-7 (2008) Article DOI: 10.1016/j.bmcl.2008.11.065 BindingDB Entry DOI: 10.7270/Q2F190PC
					More data for this Ligand-Target Pair