BDBM50378331 CHEMBL566785
SMILES: Cc1cccc(NCCCCOc2ccc(C[C@H](NS(=O)(=O)c3cccc(c3)C(F)(F)F)C(O)=O)cc2N)n1
InChI Key: InChIKey=IALCADUNFMACEG-QFIPXVFZSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50378331 (CHEMBL566785) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Catholique de Louvain Curated by ChEMBL | Assay Description Inhibition of human integrin alphav beta3 receptor by biotinylated vitronectin competitive binding assay | J Med Chem 52: 7029-43 (2009) Article DOI: 10.1021/jm901133z BindingDB Entry DOI: 10.7270/Q2GB2507 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50378331 (CHEMBL566785) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 121 | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Catholique de Louvain Curated by ChEMBL | Assay Description Inhibition of human integrin alpha2b beta3 receptor by fibrinogen competitive binding assay | J Med Chem 52: 7029-43 (2009) Article DOI: 10.1021/jm901133z BindingDB Entry DOI: 10.7270/Q2GB2507 | |||||||||||
More data for this Ligand-Target Pair |