null

SMILES: CCC(=O)Nc1cn2c(cc(cc2n1)-c1cccnc1)-c1ncc(C)cn1

InChI Key: InChIKey=AHHCJBNTWAHDNY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50378439   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase (ATP-hydrolyzing) (Streptococcus pneumoniae)	BDBM50378439 (CHEMBL565741) Show SMILES CCC(=O)Nc1cn2c(cc(cc2n1)-c1cccnc1)-c1ncc(C)cn1 Show InChI InChI=1S/C20H18N6O/c1-3-19(27)25-17-12-26-16(20-22-9-13(2)10-23-20)7-15(8-18(26)24-17)14-5-4-6-21-11-14/h4-12H,3H2,1-2H3,(H,25,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of Streptococcus pneumoniae SP-3 parE after 30 mins				Bioorg Med Chem Lett 19: 5302-6 (2009) Article DOI: 10.1016/j.bmcl.2009.07.141 BindingDB Entry DOI: 10.7270/Q23X87KD
					More data for this Ligand-Target Pair
DNA gyrase subunit B (Streptococcus pneumoniae)	BDBM50378439 (CHEMBL565741) Show SMILES CCC(=O)Nc1cn2c(cc(cc2n1)-c1cccnc1)-c1ncc(C)cn1 Show InChI InChI=1S/C20H18N6O/c1-3-19(27)25-17-12-26-16(20-22-9-13(2)10-23-20)7-15(8-18(26)24-17)14-5-4-6-21-11-14/h4-12H,3H2,1-2H3,(H,25,27)	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	255	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assay				Bioorg Med Chem Lett 19: 5302-6 (2009) Article DOI: 10.1016/j.bmcl.2009.07.141 BindingDB Entry DOI: 10.7270/Q23X87KD
					More data for this Ligand-Target Pair