new BindingDB logo
myBDB logout

BDBM50378459 NUDIPOSIDE

SMILES: COc1cc2C[C@H](CO)[C@@H](CO[C@@H]3OC[C@@H](O)[C@H](O)[C@H]3O)[C@H](c3cc(OC)c(O)c(OC)c3)c2c(OC)c1O

InChI Key: InChIKey=GWDZRGQRNHELQM-NHJKQUFYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50378459   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transcription factor HES-1


(Mus musculus)
BDBM50378459
PNG
(NUDIPOSIDE)
Show SMILES COc1cc2C[C@H](CO)[C@@H](CO[C@@H]3OC[C@@H](O)[C@H](O)[C@H]3O)[C@H](c3cc(OC)c(O)c(OC)c3)c2c(OC)c1O |r|
Show InChI InChI=1S/C27H36O12/c1-34-17-7-13(8-18(35-2)23(17)31)20-15(10-38-27-25(33)22(30)16(29)11-39-27)14(9-28)5-12-6-19(36-3)24(32)26(37-4)21(12)20/h6-8,14-16,20,22,25,27-33H,5,9-11H2,1-4H3/t14-,15-,16-,20+,22+,25-,27-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.60E+3n/an/an/an/an/an/a



Chiba University

Curated by ChEMBL


Assay Description
Inhibition of Cy3-labeled mouse recombinant Hes1 (3-281) dimer formation expressed in Escherichia coli by microplate-based assay


Bioorg Med Chem Lett 19: 5778-81 (2009)


Article DOI: 10.1016/j.bmcl.2009.07.146
BindingDB Entry DOI: 10.7270/Q26Q1Z5X
More data for this
Ligand-Target Pair