BDBM50378536 CHEMBL572115

SMILES: CCOC(=O)CN1C(=O)S\C(=C/c2ccc(o2)-c2ccc(Cl)cc2Cl)C1=O

InChI Key: InChIKey=VTGCWVJBSIBTPM-NVNXTCNLSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50378536   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha M/beta-2 (Homo sapiens (Human))	BDBM50378536 (CHEMBL572115) Show SMILES CCOC(=O)CN1C(=O)S\C(=C/c2ccc(o2)-c2ccc(Cl)cc2Cl)C1=O Show InChI InChI=1S/C18H13Cl2NO5S/c1-2-25-16(22)9-21-17(23)15(27-18(21)24)8-11-4-6-14(26-11)12-5-3-10(19)7-13(12)20/h3-8H,2,9H2,1H3/b15-8-	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.36E+4	n/a	n/a	n/a	n/a
Department of Medicine and University of Miami Curated by ChEMBL					Assay Description Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogen				Bioorg Med Chem Lett 19: 6902-6 (2009) Article DOI: 10.1016/j.bmcl.2009.10.077 BindingDB Entry DOI: 10.7270/Q2NS0VV0
					More data for this Ligand-Target Pair