BDBM50378539 CHEMBL570524

SMILES: CCOC(=O)CN1C(=O)S\C(=C/c2ccc(o2)-c2ccc(Br)cc2)C1=O

InChI Key: InChIKey=JSWQGGMWJAKFQR-DHDCSXOGSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50378539   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha M/beta-2 (Homo sapiens (Human))	BDBM50378539 (CHEMBL570524) Show SMILES CCOC(=O)CN1C(=O)S\C(=C/c2ccc(o2)-c2ccc(Br)cc2)C1=O Show InChI InChI=1S/C18H14BrNO5S/c1-2-24-16(21)10-20-17(22)15(26-18(20)23)9-13-7-8-14(25-13)11-3-5-12(19)6-4-11/h3-9H,2,10H2,1H3/b15-9-	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.04E+4	n/a	n/a	n/a	n/a
Department of Medicine and University of Miami Curated by ChEMBL					Assay Description Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogen				Bioorg Med Chem Lett 19: 6902-6 (2009) Article DOI: 10.1016/j.bmcl.2009.10.077 BindingDB Entry DOI: 10.7270/Q2NS0VV0
					More data for this Ligand-Target Pair