BDBM50378544 CHEMBL570061

SMILES: Clc1ccc(-c2ccc(C=C3SC(=O)N(CC(=O)c4ccccc4)C3=O)o2)c(Cl)c1

InChI Key: InChIKey=FCQHZVZAUCIRIJ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50378544   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha M/beta-2 (Homo sapiens (Human))	BDBM50378544 (CHEMBL570061) Show SMILES Clc1ccc(-c2ccc(C=C3SC(=O)N(CC(=O)c4ccccc4)C3=O)o2)c(Cl)c1 |w:9.8| Show InChI InChI=1S/C22H13Cl2NO4S/c23-14-6-8-16(17(24)10-14)19-9-7-15(29-19)11-20-21(27)25(22(28)30-20)12-18(26)13-4-2-1-3-5-13/h1-11H,12H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.56E+4	n/a	n/a	n/a	n/a
Department of Medicine and University of Miami Curated by ChEMBL					Assay Description Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogen				Bioorg Med Chem Lett 19: 6902-6 (2009) Article DOI: 10.1016/j.bmcl.2009.10.077 BindingDB Entry DOI: 10.7270/Q2NS0VV0
					More data for this Ligand-Target Pair