BDBM50378546 CHEMBL585139

SMILES: Cc1cccc(NC(=O)CN2C(=O)S\C(=C/c3ccc(o3)-c3ccccc3)C2=O)c1

InChI Key: InChIKey=FBUVXWJEHXSTCR-MOSHPQCFSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50378546   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha M/beta-2 (Homo sapiens (Human))	BDBM50378546 (CHEMBL585139) Show SMILES Cc1cccc(NC(=O)CN2C(=O)S\C(=C/c3ccc(o3)-c3ccccc3)C2=O)c1 Show InChI InChI=1S/C23H18N2O4S/c1-15-6-5-9-17(12-15)24-21(26)14-25-22(27)20(30-23(25)28)13-18-10-11-19(29-18)16-7-3-2-4-8-16/h2-13H,14H2,1H3,(H,24,26)/b20-13-	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.23E+4	n/a	n/a	n/a	n/a
Department of Medicine and University of Miami Curated by ChEMBL					Assay Description Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogen				Bioorg Med Chem Lett 19: 6902-6 (2009) Article DOI: 10.1016/j.bmcl.2009.10.077 BindingDB Entry DOI: 10.7270/Q2NS0VV0
					More data for this Ligand-Target Pair