BDBM50378547 CHEMBL569007

SMILES: Cc1cccc(NC(=O)CN2C(=S)S\C(=C/c3ccc(Cc4ccco4)o3)C2=O)c1

InChI Key: InChIKey=XVUIMNMSEIKAEO-UNOMPAQXSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50378547   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha M/beta-2 (Homo sapiens (Human))	BDBM50378547 (CHEMBL569007) Show SMILES Cc1cccc(NC(=O)CN2C(=S)S\C(=C/c3ccc(Cc4ccco4)o3)C2=O)c1 Show InChI InChI=1S/C22H18N2O4S2/c1-14-4-2-5-15(10-14)23-20(25)13-24-21(26)19(30-22(24)29)12-18-8-7-17(28-18)11-16-6-3-9-27-16/h2-10,12H,11,13H2,1H3,(H,23,25)/b19-12-	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a
Department of Medicine and University of Miami Curated by ChEMBL					Assay Description Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogen				Bioorg Med Chem Lett 19: 6902-6 (2009) Article DOI: 10.1016/j.bmcl.2009.10.077 BindingDB Entry DOI: 10.7270/Q2NS0VV0
					More data for this Ligand-Target Pair