null
SMILES: Nc1nnc(N)c2[nH]cnc12
InChI Key: InChIKey=UMLCZSAOYUCVKU-UHFFFAOYSA-N
PDB links: 1 PDB ID matches this monomer.
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dihydropteroate synthase (Bacillus anthracis) | BDBM50378556 (CHEMBL566922) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem | MMDB PDB Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of Bacillus anthracis DHPS expressed in Escherichia coli BL21 (DE3) after 30 mins | J Med Chem 53: 166-77 (2010) Article DOI: 10.1021/jm900861d BindingDB Entry DOI: 10.7270/Q2125TMH | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |