BDBM50378579 CHEMBL1627258
SMILES: CS(=O)(CC(=N)C(O)=O)NP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
InChI Key: InChIKey=NUXAIYMLVVYSKY-QYVSTXNMSA-N
Data: 6 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Asparagine synthetase (Homo sapiens (Human)) | BDBM50378579 (CHEMBL1627258) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC sid UniChem Similars | Article PubMed | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University Curated by ChEMBL | Assay Description Inhibition of human recombinant ASNS expressed in Sf9 cells assessed as assessed as overall inhibition constant for ammonia dependent production of i... | Bioorg Med Chem 20: 5915-27 (2012) Article DOI: 10.1016/j.bmc.2012.07.047 BindingDB Entry DOI: 10.7270/Q2MC914M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Asparagine synthetase (Homo sapiens (Human)) | BDBM50378579 (CHEMBL1627258) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC sid UniChem Similars | Article PubMed | 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University Curated by ChEMBL | Assay Description Inhibition of human recombinant ASNS expressed in Sf9 cells assessed as overall inhibition constant for glutamine dependent production of inorganic p... | Bioorg Med Chem 20: 5915-27 (2012) Article DOI: 10.1016/j.bmc.2012.07.047 BindingDB Entry DOI: 10.7270/Q2MC914M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Asparagine synthetase (Homo sapiens (Human)) | BDBM50378579 (CHEMBL1627258) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC sid UniChem Similars | Article PubMed | 280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University Curated by ChEMBL | Assay Description Inhibition of human recombinant ASNS expressed in Sf9 cells assessed as assessed as initial inhibition constant for ammonia dependent production of i... | Bioorg Med Chem 20: 5915-27 (2012) Article DOI: 10.1016/j.bmc.2012.07.047 BindingDB Entry DOI: 10.7270/Q2MC914M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Asparagine synthetase (Homo sapiens (Human)) | BDBM50378579 (CHEMBL1627258) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC sid UniChem Similars | Article PubMed | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University Curated by ChEMBL | Assay Description Inhibition of human recombinant ASNS expressed in Sf9 cells assessed as initial inhibition constant for glutamine dependent production of inorganic p... | Bioorg Med Chem 20: 5915-27 (2012) Article DOI: 10.1016/j.bmc.2012.07.047 BindingDB Entry DOI: 10.7270/Q2MC914M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Asparagine synthetase (Homo sapiens (Human)) | BDBM50378579 (CHEMBL1627258) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC sid UniChem Similars | Article PubMed | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University Curated by ChEMBL | Assay Description Inhibition of human recombinant ASNS expressed in Sf9 insect cells assessed as overall inhibition constant | Bioorg Med Chem 17: 6641-50 (2009) Article DOI: 10.1016/j.bmc.2009.07.071 BindingDB Entry DOI: 10.7270/Q2JS9RDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Asparagine synthetase (Homo sapiens (Human)) | BDBM50378579 (CHEMBL1627258) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC sid UniChem Similars | Article PubMed | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University Curated by ChEMBL | Assay Description Inhibition of human recombinant ASNS expressed in Sf9 insect cells | Bioorg Med Chem 17: 6641-50 (2009) Article DOI: 10.1016/j.bmc.2009.07.071 BindingDB Entry DOI: 10.7270/Q2JS9RDD | |||||||||||
More data for this Ligand-Target Pair |