BDBM50378669 CHEMBL591770
SMILES: N[C@@H](Cc1c(CCc2cccc3ccccc23)onc1C(O)=O)C(O)=O
InChI Key: InChIKey=WUZQANMQCPOBRP-HNNXBMFYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cystine/glutamate transporter (Homo sapiens (Human)) | BDBM50378669 (CHEMBL591770) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.17E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Montana Curated by ChEMBL | Assay Description Competitive inhibition of [3H]L-glutamate uptake at amino acid transport system xc- in human SNB19 cells by liquid scintillation counting | Bioorg Med Chem 18: 202-13 (2010) Article DOI: 10.1016/j.bmc.2009.11.001 BindingDB Entry DOI: 10.7270/Q23J3DX8 | |||||||||||
More data for this Ligand-Target Pair |