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SMILES: O=C(COc1ccccc1\N=N\c1ccccc1OCC(=O)N[C@@H](Cc1ccccc1)C(=O)OCc1ccccc1)N[C@@H](Cc1ccccc1)C(=O)OCc1ccccc1

InChI Key: InChIKey=WGQVJJVKBQXNGP-LEPJYUDRSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50378789   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Membrane-bound transcription factor site-1 protease


(Homo sapiens (Human))		BDBM50378789
PNG
(CHEMBL1170117)
Show SMILES O=C(COc1ccccc1\N=N\c1ccccc1OCC(=O)N[C@@H](Cc1ccccc1)C(=O)OCc1ccccc1)N[C@@H](Cc1ccccc1)C(=O)OCc1ccccc1 |r|
Show InChI InChI=1S/C48H44N4O8/c53-45(49-41(29-35-17-5-1-6-18-35)47(55)59-31-37-21-9-3-10-22-37)33-57-43-27-15-13-25-39(43)51-52-40-26-14-16-28-44(40)58-34-46(54)50-42(30-36-19-7-2-8-20-36)48(56)60-32-38-23-11-4-12-24-38/h1-28,41-42H,29-34H2,(H,49,53)(H,50,54)/b52-51+/t41-,42-/m0/s1
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Similars
Article
PubMed
 1.18E+4n/an/an/an/an/an/an/an/a



Indian Institute of Technology

Curated by ChEMBL


Assay Description
Inhibition of human recombinant solubule Kexin isozyme 1

Bioorg Med Chem Lett 20: 3977-81 (2010)


Article DOI: 10.1016/j.bmcl.2010.04.101
BindingDB Entry DOI: 10.7270/Q2G44R73
More data for this
Ligand-Target Pair